Antibiotic discovery and antibiotic prescribing represent two domains that both stand to benefit from artificial intelligence (AI)-driven progress in the near future.
In this article, we discuss these parallel advances and the potential future synergy between AI-enabled antibiotic discovery and AI-assisted antibiotic prescribing.
AI has accelerated and improved our capacity to discover small molecules and peptides with antibacterial activity for testing in preclinical models of infection.
AI also promises to improve the way clinicians prescribe antibiotics, assisting them throughout the complex clinical reasoning processes that guide decisions both on whether to start antibiotic therapy and which agents to prescribe.
Such a scenario could transform antibiotic therapy by enabling AI-supported, patient-specific treatment decisions while reinforcing the principles of precision medicine and antimicrobial stewardship.
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