Researchers at the California Institute of Technology (Caltech) have developed an upgraded version of a smart mask that can continuously monitor biomarkers in exhaled breath for several days.
The wearable device, powered by an integrated solar cell, could support non-invasive health monitoring and provide insights into both respiratory and metabolic conditions.
Beyond respiratory disease detection, the research team explored additional applications for the device.
In a pilot study with healthy volunteers, the mask monitored lactate levels in exhaled breath during physical activity.
Compared with other biological samples such as sweat or saliva, exhaled breath condensate can be collected passively, making the technology potentially suitable for a wide range of users, including children, older adults and critically ill patients.
The research team has also begun exploring global health applications. In collaboration with the Gates Foundation, the researchers are investigating whether simplified versions of the mask could be deployed in low-resource settings, including parts of Africa, to support screening for tuberculosis.
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