"National Cheng Kung University Medical Center focuses on critical medical treatments and values the medical safety of patients. The number of pathologic biopsy examination cases reaches 42,000 per year. If there is any error in the specimen label, replacement during transportation process, loss and erroneous placement of biopsy process, then it may cause irreversible injuries and delay of treatment to patients. Therefore, how to establish a set of e-information system capable of preventing human errors, automatically identifying errors and tracking status of pathologic biopsy specimens in order to increase the patient treatment safety and quality is the goal of this project. We thoroughly inspect the biopsy examination operation process, including the handling process before and during examination, we also convene cross-department and multi-division meetings for the entire hospital in order to find steps of high risks and to introduce the e-information system standard operation process for the entire hospital; thereby achieving the objective of complete pathologic specimen status and safety monitoring. "